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Tau
proteins
PHYSIOLOGY |
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Stabilization of microtubules,
via 3R or 4R |
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Stabilization
of microtubules, via phosphorylation |
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Microtubules,
the rails of the axonal transport
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PHYSIOPATauLOGY |
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Physiopathology
of Tau proteins:
a review |
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Slide
show on Tau |
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Biochemical parameters
of tau pathology in the human brain |
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PROGRESSION OF TAU PATHOLOGY |
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The
10 stages of Tau pathology in Alzheimer's disease |
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Progression
in Alzheimer's disease
Interaction
with APP |
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Progression
in familial Alzheimer's disease |
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Progression
in aging |
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Progression
in PSP and CBD |
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PHOSPHORYLATION |
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Role
of phosphorylation |
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Phosphorylation
sites, their kinases and references |
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Tau
kinases in a cell: a cartoon by Patrice Delobel |
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All kinases
in a table by Patrice Delobel |
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Normal
and abnormal sites of phosphorylation |
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TAUOPATHIES: the
concept |
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List
of tauopathies |
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Molecular classification
of tauopathies |
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Molecular
classification of dementing diseases |
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Tau pathology:
a marker of neurodegenerative disorders |
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4R
tauopathies |
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3R
tauopathies |
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3R versus
4R tauopathies |
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Co-factors
of tauopathies: Pin 1 |
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GENETIC |
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Tau
gene-> mRNA -> isoforms |
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Mutations
on tau gene.
TABLE,
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| Mutations
location on tau |
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Haplotypes H1 and H2 |
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Signalling pathways |
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Other
molecular aspects
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